| Full text | |
| Author(s): Show less - |
Morais, Felipe Alves
;
Pereira, Alexandre
;
Pietro Pereira, Aparecida Santo
;
Moreli, Marcos Lazaro
;
Aranha Camargo, Luis Marcelo
;
Nardi, Marcello Schiavo
;
Tofoli, Cristina Farah
;
Araujo, Jansen
;
Dutra, Lilia Mara
;
Ometto, Tatiana Lopes
;
Hurtado, Renata
;
de Jesus Maues, Fabio Carmona
;
Hinke, Tiene Zingano
;
Mahmud, Sati Jaber
;
Lima, Monica Correia
;
Moraes Figueiredo, Luiz Tadeu
;
Durigon, Edison Luiz
Total Authors: 17
|
| Document type: | Journal article |
| Source: | ADVANCES IN VIROLOGY; v. 2016, p. 6-pg., 2016-01-01. |
| Abstract | |
Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region) in Rondonia state and a subtropical (Atlantic Rain Forest) region in Sao Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%), of which 62 were from the tropical area (5.8%) and 20 from the subtropical area (8.3%), tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil. (AU) | |
| FAPESP's process: | 05/01603-4 - Serological detection of hantavirus in wild and human animal samples in the state of São Paulo by Western Blotting and ELISA assay using recombinant protein developed in Brazil |
| Grantee: | Felipe Alves Morais |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |