Phytochemical Analysis and Antifungal Activity of Extracts from Leaves and Fruit Residues of Brazilian Savanna Plants Aiming Its Use as Safe Fungicides

Author(s)

Breda, Caroline Alves ; Gasperini, Alessandra Marcon ; Garcia, Vera Lucia ; Monteiro, Karin Maia ; Bataglion, Giovana Anceski ; Eberlin, Marcos Nogueira ; Teixeira Duarte, Marta Cristina

• Document type: Journal article
• Source: NATURAL PRODUCTS AND BIOPROSPECTING; v. 6, n. 4, p. 10-pg., 2016-08-01.

Abstract

The increasing demand for safe food without preservatives or pesticides residues has encouraged several studies on natural products with antifungal activity and low toxicity. In this study, ethanolic extracts from leaves and fruit residues (peel and seeds) of three Brazilian savanna species (Acrocomia aculeata, Campomanesia adamantium and Caryocar brasiliense) were evaluated against phytopathogenic fungi. Additionally, the most active extract was chemically characterized by ESI-MS and its oral acute toxicity was evaluated. Extracts from C. brasiliense (pequi) peel and leaves were active against Alternaria alternata, Alternaria solani and Venturia pirina with minimal inhibitory concentrations between 350 and 1000 mu g/mL. When incorporated in solid media, these extracts extended the lag phase of A. alternata and A. solani and reduced the growth rate of A. solani. Pequi peel extract showed better antifungal activity and their ESI-MS analysis revealed the presence of substances widely reported as antifungal such as gallic acid, quinic acid, ellagic acid, glucogalin and corilagin. The oral acute toxicity was relatively low, being considered safe for use as a potential natural fungicide. [GRAPHICS] . (AU)

• FAPESP's process: 12/21395-0 - Molecular characterization of sedimentary organic matter in the Estuary-Lagoon System Cananéia-Iguape by Fourier transform ion cyclotron resonance mass spectrometry
• Grantee: Giovana Anceski Bataglion
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 11/19057-7 - Activity of extracts from leaves and residue of cerrado fruits against fruit phytopathogenic fungi.
• Grantee: Caroline Alves Breda
• Support Opportunities: Scholarships in Brazil - Doctorate