New Genomic Approaches to Enhance Biomass Degradation by the Industrial Fungus Trichoderma reesei

Author(s):Show less -

de Paula, Renato Graciano ; Campos Antonieto, Amanda Cristina ; Costa Ribeiro, Liliane Fraga ; Carraro, Claudia Batista ; Vieira Nogueira, Karoline Maria ; Borges Lopes, Douglas Christian ; Silva, Alinne Costa ; Zerbini, Mariana Taise ; Pedersoli, Wellington Ramos ; Costa, Mariana do Nascimento ; Silva, Roberto Nascimento

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF GENOMICS; v. 2018, p. 17-pg., 2018-01-01.

Abstract

The filamentous fungi Trichoderma reesei is one of the most well-studied cellulolytic microorganisms. It is the most important fungus for the industrial production of enzymes to biomass deconstruction being widely used in the biotechnology industry, mainly in the production of biofuels. Here, we performed an analytic review of the holocellulolytic system presented by T. reesei as well as the transcriptional and signaling mechanisms involved with holocellulase expression in this fungus. We also discuss new perspectives about control of secretion and cellulase expression based on RNA-seq and functional characterization data of T. reesei growth in different carbon sources, which comprise glucose, cellulose, sophorose, and sugarcane bagasse. (AU)

• FAPESP's process: 16/23233-9 - Characterization of calcium-dependent signaling pathway in the secretion and cellulase expression by Trichoderma reesei (Hypocrea jecorina
• Grantee: Renato Graciano de Paula
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 16/20358-5 - Systems biology analysis of the role of protein kinase A (PKA), in the fungus Trichoderma reesei by phosphoproteomic
• Grantee: Liliane Fraga Costa Ribeiro
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 17/04206-3 - Elucidation of cellular signaling pathways mediated by protein kinase A (PKA), MAPK and calcium during expression and secretion of cellulases by the fungus Trichoderma reesei
• Grantee: Roberto do Nascimento Silva
• Support Opportunities: Regular Research Grants