The relationship between heart rate and VO2 in moderate-to-severe asthmatics

Author(s)

Rodrigues Mendes, Felipe A. ; Teixeira, Renata Nakata ; Martins, Milton A. ; Cukier, Alberto ; Stelmach, Rafael ; Medeiros, Wladimir Musetti ; Carvalho, Celso R. F.

• Document type: Journal article
• Source: JOURNAL OF ASTHMA; v. 57, n. 7, p. 9-pg., 2019-07-02.

Abstract

Objective: The main purpose of this study was to evaluate whether the %HRR-%VO2R relationship and %HRR-VO2peak relationship are affected in patients with moderate or severe asthma and whether airway obstruction and aerobic capacity influence these relationships. Methods: A linear regression was calculated using the paired %VO2R-%HRR and %VO2peak-%HRR for 93 subjects with asthma. The mean slope and y-intercept were calculated and compared with the line of identity (y-intercept = 0, slope = 1) for all patients and subgroups for the following conditions: low and normal VO2peak and low and normal FEV1. Results: The slope and intercepts of %VO2R-%HRR were similar to the line of identity for all groups (p > 0.05), and the regressions between %HRR and %VO2peak did not coincide with the line of identity for all groups (p < 0.05). There were no associations between the intercepts of the %HRR-VO2peak and the %HRR-%VO2R relationship with the VO2peak (p > 0.05) or FEV1 (p > 0.05). Conclusions: This is the first study to confirm a constant equivalence between %HRR and %VO2R in outpatients with moderate or severe asthma. Our data also suggest that the relationship between %HRR and %VO2peak is unreliable. These results support the use of %HRR in relation to %VO2R to estimate exercise intensity in this population, independently of the pulmonary function and fitness level. (AU)

• FAPESP's process: 09/53904-9 - Effects of environment and lifestyle on asthma and chronic obstructive pulmonary disease: studies with experimental animals and people with asthma
• Grantee: Milton de Arruda Martins
• Support Opportunities: Research Projects - Thematic Grants