| Full text | |
| Author(s): |
Mariz, Bruno Augusto Linhares Almeida
;
Tager, Elena Maria Jose Roman
;
Fernandez, Carlos Cordon
;
de Almeida, Oslei Paes
;
Carlos, Roman
Total Authors: 5
|
| Document type: | Journal article |
| Source: | Head and Neck Pathology; v. 15, n. 3, p. 8-pg., 2020-10-21. |
| Abstract | |
Carney complex (CNC) is a rare, autosomal dominant multiple neoplasia syndrome. Although cutaneous myxomas commonly occur in CNC patients, intraoral myxomas are extremely rare. We present a case of a palatal myxoma in a 21-year-old female patient with CNC, along with a review of the pertinent literature. She presented with a sessile nodule on the hard palate that microscopically showed a multilobulated and highly vascularized myxomatous tissue composed of loosely-arranged spindle, polygonal, and stellate cells, suggestive of myxoid neurofibroma. Six years after the oral lesion was removed, she presented with a growth hormone (GH)-producing pituitary adenoma, a cardiac myxoma, two cutaneous myxomas on the lower abdomen area, and one myxoma in the vaginal mucosa. Therefore, the final diagnosis of the palatal lesion was of a soft tissue myxoma related to CNC. The patient remains on close follow-up, with no recurrences of the palatal myxoma after 7 years. (AU) | |
| FAPESP's process: | 18/24715-2 - FGF-2, FGFR-1, PI3K, Akt and COX-2 expression in Oral Leucoplakia, primary and metastatic Oral Squamous Cell Carcinoma |
| Grantee: | Bruno Augusto Linhares Almeida Mariz |
| Support Opportunities: | Scholarships in Brazil - Doctorate |