Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Relationship between chronic pain, depressive symptoms, and functional disability in community-dwelling older adults: mediating role of frailty

Full text
Author(s):
Flávia Silva Arbex Borim [1] ; Daniela de Assumpção [2] ; Mônica Sanches Yassuda ; Henrique Trajano de Moraes Costa [4] ; Samila Sathler Tavares Batistoni ; Anita Liberalesso Neri [6] ; Richard C. Oude Voshaar ; Ivan Aprahamian
Total Authors: 8
Affiliation:
[1] Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Programa de pós-graduação em Gerontologia - Brasil
[2] Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Programa de pós-graduação em Gerontologia - Brasil
[4] Faculdade de Medicina de Jundiaí. Department of Internal Medicine. Group of Investigation on Multimorbidity and Mental Health in Aging - Brasil
[6] Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Programa de pós-graduação em Gerontologia - Brasil
Total Affiliations: 8
Document type: Journal article
Source: Einstein (São Paulo); v. 21, 2023-12-15.
Abstract

ABSTRACT Objective To evaluate the direct and indirect effects of chronic pain, depressive symptoms, frailty components, and functional disability through a pathway analysis approach in a sample of community-dwelling older adults. Methods Data of 419 participants were cross-sectionally evaluated for the presence of depressive symptoms (Geriatric Depression Scale [15 items]), physical frailty components (phenotype criteria), chronic pain, and limitations in performing instrumental activities of daily living (functional disability scale by Lawton and Brody). Structural equation modeling via path analysis was used to explore the direct and indirect effects among these four variables. Statistical significance was set at p<0.05. Results Of the total participants, 69.8% were women and 59.3% had low education (1-4 years); the mean age was 80.3±4.6 years. Chronic pain and depressive symptoms were directly related and were associated to frailty. The number of frailty components and depressive symptoms were directly associated with functional disability. Frailty had an indirect effect on the association between chronic pain, depressive symptoms, and functional disabilities. Conclusion The pathway from chronic pain and depressive symptoms to functional disability is potentially mediated by the number of frailty components. (AU)

FAPESP's process: 16/00084-8 - Longitudinal study of the Campinas and Ermelino Matarazzo cohorts of the FIBRA study: predictors and outcomes of frailty among the elderly in Brazil
Grantee:Monica Sanches Yassuda
Support Opportunities: Research Projects - Thematic Grants