| Full text | |
| Author(s): |
Berlinck, Roberto G. S.
;
Skellam, Elizabeth
Total Authors: 2
|
| Document type: | Journal article |
| Source: | Journal of Natural Products; v. N/A, p. 15-pg., 2024-11-15. |
| Abstract | |
Solanapyrones are metabolites bearing a 3,4-dehydrodecalin moiety isolated from cultures of different fungi that are associated with plant diseases. Research on solanapyrones resulted in the first report of a Diels-Alderase enzyme implicated in natural product biosynthesis related to the formation of the 3,4-dehydrodecalin core. In addition, several total syntheses of solanapyrones have been reported, which are also connected with the formation of the characteristic cycloaddition-derived 3,4-dehydrodecalin moiety. This Review provides the first comprehensive overview on the chemistry, biosynthesis, and biological activities of solanapyrones under the theme of synthetic and biosynthetic research progress on cycloaddition-derived secondary metabolites. (AU) | |
| FAPESP's process: | 19/17721-9 - The role of Chemistry in holobiont adaptation |
| Grantee: | Roberto Gomes de Souza Berlinck |
| Support Opportunities: | Research Projects - Thematic Grants |