In utero exposure to air pollution lowers erythrocyte antioxidant defense and decreases weight in adult mice

Abe, Karina Camasmie; Brandao, Leticia de Campos; Tufik, Sergio; do Nascimento Saldiva, Paulo Hilario; D'Almeida, Vania

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

In utero exposure to air pollution lowers erythrocyte antioxidant defense and decreases weight in adult mice

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Author(s):	Abe, Karina Camasmie ^[1] ; Brandao, Leticia de Campos ^[1] ; Tufik, Sergio ^[1] ; do Nascimento Saldiva, Paulo Hilario ^[2] ; D'Almeida, Vania ^[1] Total Authors: 5
Affiliation:	^[1] Univ Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo - Brazil ^[2] Univ Sao Paulo, Dept Pathol, Lab Air Pollut, Sao Paulo - Brazil Total Affiliations: 2
Document type:	Journal article
Source:	ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 32, n. 2, p. 315-318, SEP 2011.
Web of Science Citations:	0
Abstract
In this study, we tested the influence of ambient air pollution on different phases of development of adult mice. With respect to adult weight, the animals that had spent their in utero period exposed to pollution showed less weight gain over their lifetime, as well as lower activity levels of the antioxidant enzymes catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPx). Our study suggests that contact with atmospheric pollutants during the foetal period produces important changes on enzymatic erythrocyte antioxidant defense and weight in adult mice. (C) 2011 Elsevier B.V. All rights reserved. (AU)

FAPESP's process:	07/07624-9 - Maternal-fetal programming: impact on biochemical, epigenetic and behavioral parameters
Grantee:	Vânia D'Almeida
Support Opportunities:	Regular Research Grants

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