| Full text | |
| Author(s): |
Neto, Nilton F. Azevedo
;
Miranda, Felipe S.
;
Moreira Jr, Pedro W. P.
;
Gomes, Marcelo P.
;
Alves-Junior, Clodorimo
;
Koga-Ito, Cristiane Y.
;
Pessoa, Rodrigo S.
Total Authors: 7
|
| Document type: | Journal article |
| Source: | JOURNAL OF PHYSICS D-APPLIED PHYSICS; v. 58, n. 1, p. 12-pg., 2025-01-06. |
| Abstract | |
Plasma-activated saline (PAS) holds immense potential for diverse applications, including antimicrobial activity, anti-inflammatory effects, and cancer therapy. This study introduces a novel approach utilizing a serially associated hybrid plasma discharge system, which combines dielectric barrier discharge (DBD) with a gliding arc plasma jet (GAPJ), to enhance the production of reactive oxygen and nitrogen species (RONS) in saline water. The serial configuration of DBD and GAPJ effectively amplifies the generation of RONS, as confirmed by optical emission spectroscopy, which revealed unique emissions associated with nitrogen and oxygen ions. Significant changes in the physicochemical properties of saline were observed, including reductions in pH and increases in oxidation-reduction potential and total dissolved solids, particularly during the initial activation phase. Real-time UV-Vis spectroscopy revealed the formation of key RONS such as hydrogen peroxide (H2O2), ozone (O3), nitrite (NO2-), and nitrate (NO3-), with distinct absorption bands emerging in the UV region. Raman spectroscopy further confirmed the impact of plasma treatment on the molecular structure of saline, showing a weakening of the hydrogen-bonding network. This work offers new insights into PAS production using the serial association of DBD and GAPJ, advancing its potential for various therapeutic applications. (AU) | |
| FAPESP's process: | 23/02268-2 - Generation and characterization of different liquids activated with plasma for use in endodontic treatment |
| Grantee: | Nilton Francelosi Azevedo Neto |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 21/14181-3 - Development and study of a plasma system generated by dielectric barrier discharge (DBD) for continuous activation of liquids applied in dental treatments |
| Grantee: | Felipe de Souza Miranda |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 19/05856-7 - Use of low temperature atmospheric pressure plasma in dentistry: from laboratory bench to clinics |
| Grantee: | Cristiane Yumi Koga Ito |
| Support Opportunities: | Research Projects - Thematic Grants |