Transformative nanobioplasmonic effects: Toxicological implications of plasmonic silver nanoparticles in aquatic biological models

Author(s)

Queiroz, Lucas G. ; Faustino, Leandro A. ; de Oliveira, Paulo F. M. ; Pompeo, Marcelo ; de Torresi, Susana I. Cordoba

• Document type: Journal article
• Source: Science of The Total Environment; v. 954, p. 11-pg., 2024-10-01.

Abstract

Silver nanoparticles (AgNPs) present unique properties, such as the induced localized surface plasmon resonance (LSPR) provoked under illumination with a proper wavelength, allowing these nanomaterials to be applied in fields such as catalysis and biomedicine. The study of AgNPs is also highly relevant from the environmental pollution viewpoint due to their high production and application in commercial products. Consequently, AgNPs reach aquatic environments and can be plasmonically stimulated under natural light conditions. This study investigates the toxic effects promoted by AgNPs under plasmonic excitation on the survival and physiology of the crustacean Daphnia similis. . Two AgNP shapes (spherical and triangular) with plasmon bands absorbing in different spectral regions in the visible range were studied. The organisms were exposed to different AgNP concentrations under five different light conditions. Survival and changes in enzymatic biomarkers of oxidative stress and lipid storage were evaluated. Under LSPR conditions, we observed increased lethality for both AgNP shapes. LSPR effects of AgNPs showed mortality 2.6 and 1.7 times higher than the treatment under dark conditions for spherical and triangular morphologies respectively. The enzymatic assays demonstrated that plasmonic treatments triggered physiological responses. Significantly decreased activities were observed exclusively under LSPR conditions for both AgNP shapes. Considering all treatments, spherical AgNPs showed lower LC50 50 values than triangular ones, indicating their higher toxic potential. Our results demonstrate that LSPR AgNPs can induce biological responses associated with oxidative stress and survival. Therefore, this study highlights the potential risks of environmental contamination by plasmonically active metallic nanomaterials. These materials can enhance their toxicity when light-excited, yet the results also indicate promising opportunities for light-based therapies. (AU)

• FAPESP's process: 21/00675-4 - Tying up materials for electrochemical energy storage and catalysis
• Grantee: Roberto Manuel Torresi
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 22/13146-2 - Biomaterials based on conductive and biodegradable Polymers and bionanoplasmonics
• Grantee: Lucas Gonçalves Queiroz
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 20/14955-6 - Designing the next generation of advanced multicomponent materials through mechanochemical synthesis
• Grantee: Paulo Filho Marques de Oliveira
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 22/04604-7 - Plasmonic contributions to N2 and CO2 co-electrolysis
• Grantee: Leandro Augusto Faustino
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 18/13492-2 - Synthetic and natural scaffolds applied to regenerative medicine
• Grantee: Luiz Henrique Catalani
• Support Opportunities: Research Projects - Thematic Grants