| Full text | |
| Author(s): |
de Souza, Gabriel O.
;
dos Santos, Willian O.
;
Donato, Jose
Total Authors: 3
|
| Document type: | Journal article |
| Source: | TRENDS IN ENDOCRINOLOGY AND METABOLISM; v. 35, n. 6, p. 3-pg., 2024-06-10. |
| Abstract | |
Obesity is associated with dysfunctions in hypothalamic neurons that regulate metabolism, including agouti-related protein (AgRP)-expressing neurons. In a recent article, Zhang et al. demonstrated that either dietor genetically induced obesity promoted iron accumulation specifically in AgRP neurons. Preventing iron overload in AgRP neurons mitigated diet-induced obesity and related comorbidities in male mice. (AU) | |
| FAPESP's process: | 20/15262-4 - Study of cellular factors that affects energy balance through AgRP neurons: role of connexin 43 and mTORC1 pathway |
| Grantee: | Gabriel Orefice de Souza |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 20/01318-8 - Central nervous system as a target of growth hormone for the regulation of multiple biological functions |
| Grantee: | Jose Donato Junior |
| Support Opportunities: | Research Projects - Thematic Grants |