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Photocatalytic Multicomponent Carboxylation of Olefins and Sulfinate Salts with 13CO2

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Author(s):
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Lyonnet, Julien R. ; Velasco-Rubio, Alvaro ; Abrams, Roman ; Phan, Ha ; Muhlfenzl, Kim ; Chen, Xuemeng ; Cerveri, Alessandro ; Correia, Jose TiagoM. ; Paixao, Marcio W. ; Elmore, Charles S. ; Martin, Ruben
Total Authors: 11
Document type: Journal article
Source: ACS CATALYSIS; v. 14, n. 24, p. 6-pg., 2024-12-06.
Abstract

Herein, we describe a photoinduced multicomponent catalytic carboxylation protocol that streamlines the access to 13C-labeled carboxylic acids from simple olefin precursors, sulfinate salts and 13CO2. Site selectivity is dictated by the radical philicity of the starting precursors and reaction intermediates, resulting in either a four-component or a five-component endeavor. The method is characterized by its simplicity and flexibility across a wide number of coupling counterparts (AU)

FAPESP's process: 19/01560-6 - Nickel-catalyzed intermolecular dicarbofunctionalization of unactivated alkenes, employing CO2 and radical precursors
Grantee:José Tiago Menezes Correia
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor