Patient Blood Management Program Implementation: Comprehensive Recommendations and Practical Strategies

Author(s):Show less -

Cespedes, Isabel Cristina ; Figueiredo, Maria Stella ; Hossne Jr, Nelson Americo ; Suriano, italo Capraro ; Rodrigues, Rita de Cassia ; Barros, Melca Maria Oliveira ; Neto, Manoel Antonio de Paiva ; Atallah, Fernanda Chohfi ; Benini, Barbara Burza ; Gonzalez, Adriano Miziara ; Sparapani, Fabio Veiga de Castro ; de Barros Jr, Newton ; Carneiro, Ieda Aparecida ; Sarto, Celina Mayumi Morita ; Motoyama, Caio Sussumu de Macedo ; Sacchi, Leonardo ; Piovezan, Victor ; de Almeida, Simone Luna ; Pereira-Rufino, Lais da Silva ; Rocco, Isadora Salvador ; Guizilini, Solange ; Mansur, Nacime Salomao ; Arakaki, Jaquelina Sonoe Ota ; dos Santos, Antonio Alceu ; Panfilio, Carlos Eduardo

• Document type: Journal article
• Source: Revista Brasileira de Cirurgia Cardiovascular; v. 39, n. 5, p. 10-pg., 2024-01-01.

Abstract

Introduction: Blood transfusion is one of the most common medical practices worldwide. However, current scientific literature has shown that the immunomodulatory effects of blood transfusion are associated with an increased likelihood of infection, prolonged hospitalization, and morbimortality. Also, it means high costs for healthcare systems. Methods: In this context, acknowledging that blood transfusions are essentially heterologous cell transplantations, the use of therapeutic options has gained strength and is collectively known as the patient blood management (PBM) program. PBM is an approach based on three main pillars: (1) treating anemias and coagulopathies in an optimized manner, especially in the preoperative period; (2) optimizing perioperative hemostasis and the use of blood recovery systems to avoid the loss of the patient's blood; (3) anemia tolerance, with improved oxygen delivery and reduced oxygen demand, particularly in the postoperative period. Results: Current scientific evidence supports the effectiveness of PBM by reducing the need for blood transfusions, decreasing associated complications, and promoting more efficient and safer blood management. Thus, PBM not only improves clinical outcomes for patients but also contributes to the economic sustainability of healthcare systems. Conclusion:The aim of this review was to summarize PBM strategies in a comprehensive, evidence-based approach through a systematic and structured model for PBM implementation in tertiary hospitals. The recommendations proposed herein are from researchers and experts of a high-complexity university hospital in the network of the Sistema & Uacute;nico de Sa & uacute;de, presenting itself as a strategy that can be followed as a guideline for PBM implementation in other settings. (AU)

• FAPESP's process: 22/15920-7 - Analysis of epigenetic effects associated with blood transfusions in humans
• Grantee: Isabel Cristina Céspedes
• Support Opportunities: Regular Research Grants