| Full text | |
| Author(s): |
Santos, Gabriel Siqueira dos
;
da Costa, Andre Luiz Mota
;
Martins, Mariana Castilho
;
Teixeira, Rodrigo Hidalgo Friciello
;
Sartori, Luciana
;
Gaeta, Natalia Carrillo
;
Souza, Gisele Oliveira de
;
Neto, Jose Soares Ferreira
;
Heinemann, Marcos Bryan
Total Authors: 9
|
| Document type: | Journal article |
| Source: | Veterinary Microbiology; v. 307, p. 5-pg., 2025-08-01. |
| Abstract | |
Carbapenemase-producing Escherichia coli are frequently related to healthcare-associated infections. Still, those have been reported from variable sources, including wild and zoo animals, posing a substantial threat to the conservation of animal species vulnerable to extinction. In this study, we reported an NDM-5-producing E. coli ST 48 isolated from rectal swab collected on April 21st, 2024 from a healthy Giant Anteater (Myrmecophaga tridactyla) in a Brazilian Zoo. The E. coli strain showed antimicrobial-resistant genes to quinolones, tetracyclines, and beta-lactams, including carbapenems, cephalosporins, and penicillins, besides a wide range of virulence factors encoding genes. Phylogenomic analysis showed that the NDM-5-producing E. coli ST48 strain clustered with lineages from Myanmar and China. Its blaNDM-5 genetic context shared insertion sequences and adjacent genes with other ST48 strains. This is the first report of NDM-5-producing E. coli isolated from a zoo animal in Brazil, highlighting the potential to species conservation and the importance of monitoring antimicrobialresistant bacteria in zoo animals. (AU) | |
| FAPESP's process: | 20/15008-0 - Evaluation of bats in urban-rural interfaces: heavy metal contamination, antimicrobial resistance, and microorganisms with zoonotic potential |
| Grantee: | Natália Carrillo Gaeta |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |