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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparison of oral versus sublingual piroxicam during postoperative pain management after lower third molar extraction

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Author(s):
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Trindade, P. A. K. [1] ; Giglio, F. P. M. ; Colombini-Ishikiriama, B. L. ; Calvo, A. M. ; Modena, K. C. S. ; Ribeiro, D. A. ; Dionisio, T. J. ; Brozoski, D. T. ; Lauris, J. R. P. ; Faria, F. A. C. ; Santos, C. F.
Total Authors: 11
Affiliation:
[1] Univ Sao Paulo, Discipline Pharmacol, Bauru Sch Dent, BR-17012901 Bauru, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: International Journal of Oral and Maxillofacial Surgery; v. 40, n. 3, p. 292-297, MAR 2011.
Web of Science Citations: 8
Abstract

In this study, 53 patients received piroxicam, administered orally or sublingually, after undergoing removal of symmetrically positioned lower third molars, during two separate appointments. This study used a randomized, blind, cross-over protocol. Objective and subjective parameters were recorded for comparison of postoperative results for 7 days after surgery. Patients treated with oral or sublingual piroxicam reported low postoperative pain scores. The patients who received piroxicam orally took a similar average amount of analgesic rescue medication compared with patients who received piroxicam sublingually (p > 0.05). Patients exhibited similar values for mouth opening measured just before surgery and immediately following suture removal 7 days later (p > 0.05), and showed no significant differences between routes of piroxicam administration for swelling control during the second or seventh postoperative days (p > 0.05). In summary, pain, trismus and swelling after lower third molar extraction, independent of surgical difficulty, could be controlled by piroxicam 20 mg administered orally or sublingually and no significant differences were observed between the route of delivery used in this study. (AU)

FAPESP's process: 09/15372-5 - Interaction between the renin-angiotensin system and the vascular endothelial growth factor in the experimentally-induced periodontal disease in rats
Grantee:Daniel Thomas Brozoski
Support Opportunities: Scholarships in Brazil - Post-Doctoral