| Full text | |
| Author(s): |
Suarez, Willian Toito
[1]
;
Pessoa-Neto, Osmundo Dantas
[2]
;
Janegitz, Bruno Campos
[2]
;
Vieira, Heberth Juliano
[3]
;
Faria, Ronaldo Censi
[2]
;
Fatibello-Filho, Orlando
[2]
Total Authors: 6
|
| Affiliation: | [1] Univ Fed Vicosa, Dept Quim, Ctr Ciencias Exatas & Tecnol, Vicosa, MG - Brazil
[2] Univ Fed Sao Carlos, Dept Quim, Ctr Ciencias Exatas & Tecnol, BR-13560970 Sao Carlos, SP - Brazil
[3] Fundacao Univ Fed Grande Dourados, Fac Ciencias Exatas & Tecnol, Dourados, MS - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Analytical Letters; v. 44, n. 14, p. 2394-2405, 2011. |
| Web of Science Citations: | 15 |
| Abstract | |
A novel flow injection procedure to determine N-acetylcysteine and captopril in pharmaceutical formulations is proposed. The flow procedure developed was based on oxidation of the analytes by Fe(III) in acidic medium and subsequent reaction of the Fe(II) generated with excess hexacyanoferrate(III) to produce soluble Prussian blue (KFe{[}Fe(CN)(6)]) measured at 700 nm. Detection limits of 1.0 x 10(-5) mol L(-1) and 3.0 x 10(-5) mol L(-1) for N-acetylcysteine and captopril, respectively, were found. The sample throughput was 70 h(-1) for both analytes and the results obtained were in agreement at a 95% confidence level with those obtained using reference methods. (AU) | |
| FAPESP's process: | 08/09893-0 - DEVELOPMENT OF BIOSENSORS USING CARBON NANOTUBE AND NANOPARTICLES |
| Grantee: | Bruno Campos Janegitz |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 08/11151-1 - Application of analytical microsystems constructed with LTCC (Low temperature Co-fired ceramics) for glucose, cholesterol and urea determination by means of enzimatic reactions with chemiluminescence and spectrophotometric detection |
| Grantee: | Willian Toito Suarez |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |