| Full text | |
| Author(s): |
Pinto Vilela, Fernanda Maria
[1]
;
Fonseca, Yris Maria
[1]
;
Vicentini, Fabiana T. M. C.
[1]
;
Vieira Fonseca, Maria Jose
[1]
;
Henriques do Amaral, Maria da Penha
[2]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Ciencias Farmaceut, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Univ Fed Juiz de Fora, Fac Farm & Bioquim, Dept Farmaceut, BR-36036900 Juiz De Fora, MG - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Química Nova; v. 34, n. 5, p. 879-883, 2011. |
| Web of Science Citations: | 11 |
| Abstract | |
An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention. (AU) | |
| FAPESP's process: | 09/00924-2 - Evaluation of in vivo safety of ultraviolet filters in sunscreen formulation |
| Grantee: | Fernanda Maria Pinto Vilela |
| Support Opportunities: | Scholarships in Brazil - Master |