| Full text | |
| Author(s): |
Santos, Maria Teresa
[1]
;
Guare, Renata
;
Leite, Mariana
;
Ferreira, Maria Cristina
;
Nicolau, Jose
[2]
Total Authors: 5
|
| Affiliation: | [1] Univ Cruzeiro Sul, Persons Disabil Div, BR-04605001 Sao Paulo - Brazil
[2] Univ Sao Paulo, Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | JOURNAL OF ORAL PATHOLOGY & MEDICINE; v. 39, n. 10, p. 770-774, NOV 2010. |
| Web of Science Citations: | 16 |
| Abstract | |
Background: Previous studies reported alterations in salivary flow rate and biochemical parameters of saliva in cerebral palsy (CP) individuals; however, none of these considered the type of neuromotor abnormality among CP individuals, thus it remains unclear whether the different anatomical and extended regions of the brain lesions responsible for the neurological damage in CP might include disruption of the regulatory mechanism of saliva secretion as part of the encephalopathy. The aim of this study was to evaluate salivary flow rate, pH and buffer capacity in saliva of individuals with CP, aged 3-16 years, with spastic neuromotor abnormality type and clinical patterns of involvement. Methods: Sixty-seven individuals with CP spasticity movement disorder, were divided in two groups according to age (3-8- and 9-16-years-old) and compared with 35 sibling volunteers with no neurological damage, divided in two groups according to age (3-8- and 9-16-years-old). Whole saliva was collected under slight suction and pH and buffer capacity were determined using a digital pHmeter. Buffer capacity was measured by titration using 0.01N HCL, and flow rate was calculated in ml/min. Results: In both age groups studied, whole saliva flow rate, pH and buffer capacity were significantly lower in the spastic CP group (P < 0.05). The clinical patterns of involvement did not influence the studied parameters. Conclusion: These findings show that individuals with spastic cerebral palsy present lower salivary flow rate, pH and buffer capacity that can increase the risk of oral disease in this population. (AU) | |
| FAPESP's process: | 08/00960-6 - Autonomic response in individuals with cerebral palsy |
| Grantee: | Maria Teresa Botti Rodrigues dos Santos |
| Support Opportunities: | Regular Research Grants |