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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys

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Author(s):
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Kessler, Ronald C. [1] ; McLaughlin, Katie A. [1] ; Green, Jennifer Greif [2] ; Gruber, Michael J. [1] ; Sampson, Nancy A. [1] ; Zaslavsky, Alan M. [1] ; Aguilar-Gaxiola, Sergio [3] ; Alhamzawi, Ali Obaid [4] ; Alonso, Jordi [5, 6] ; Angermeyer, Matthias [7] ; Benjet, Corina [8] ; Bromet, Evelyn [9] ; Chatterji, Somnath [10] ; de Girolamo, Giovanni [11] ; Demyttenaere, Koen [12] ; Fayyad, John [13] ; Florescu, Silvia [14] ; Gal, Gilad ; Gureje, Oye [15] ; Maria Haro, Josep [16] ; Hu, Chi-yi [17, 18] ; Karam, Elie G. [13] ; Kawakami, Norito [19] ; Lee, Sing [20] ; Lepine, Jean-Pierre [21] ; Ormel, Johan [22] ; Posada-Villa, Jose [23] ; Sagar, Rajesh [24] ; Tsang, Adley [20] ; Uestuen, T. Bedirhan [10] ; Vassilev, Svetlozar [25] ; Viana, Maria Carmen [26] ; Williams, David R. [27]
Total Authors: 33
Affiliation:
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[1] Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 - USA
[2] Boston Univ, Sch Educ, Boston, MA 02215 - USA
[3] Univ Calif Davis, Ctr Hlth Dispar, Davis, CA 95616 - USA
[4] Al Qadisia Univ, Coll Med, Diwania Governate - Iraq
[5] CIBER Epidemiol & Salud Publ CIBERESP, Barcelona - Spain
[6] IMIM Hosp Mar, Inst Municipal Invest Med, Hlth Serv Res Unit, Barcelona - Spain
[7] Ctr Publ Mental Hlth, Goesing Wagram - Austria
[8] Natl Inst Psychiat, Mexico City, DF - Mexico
[9] SUNY Stony Brook, Dept Psychiat, New York, NY - USA
[10] World Hlth Org, Geneva - Switzerland
[11] IRCCS Ctr S Giovanni Dio Fatebenefratelli, Brescia - Italy
[12] Univ Hosp Gasthuisberg, Dept Psychiat, B-3000 Louvain - Belgium
[13] Balamand Univ, St George Hosp Univ Med Ctr, Fac Med, IDRAAC, MIND, Beirut - Lebanon
[14] Natl Sch Publ Hlth & Hlth Serv Management, Publ Hlth Res & Evidence Based Med Dept, Bucharest - Romania
[15] Univ Coll Hosp, Ibadan - Nigeria
[16] CIBER Salud Mental, Fundacio Sant Joan de Deu, Barcelona - Spain
[17] Shenzhen Inst Mental Hlth, Shenzhen - Peoples R China
[18] Shenzhen Kangning Hosp, Shenzhen - Peoples R China
[19] Univ Tokyo, Sch Publ Hlth, Dept Mental Hlth, Tokyo 1138654 - Japan
[20] Chinese Univ Hong Kong, Shatin, Hong Kong - Peoples R China
[21] Univ Paris Diderot & Paris Descartes, Hop Lariboisiere Fernand Widal, Assistance Publ Hop Paris, INSERM, CNRS, U 705, UMR 7157, Paris - France
[22] Univ Groningen, Univ Med Ctr Groningen, Univ Ctr Psychiat, Dept Psychiat & Psychiat Epidemiol, NL-9713 AV Groningen - Netherlands
[23] Colegio Mayor Cundinamarca Univ, Minist Social Protect, Bogota - Colombia
[24] All India Inst Med Sci, Dept Psychiat, New Delhi - India
[25] New Bulgarian Univ, Sofia - Bulgaria
[26] Univ Sao Paulo, Sch Med, Inst Psychiat, Sect Psychiat Epidemiol, Sao Paulo - Brazil
[27] Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 - USA
Total Affiliations: 27
Document type: Journal article
Source: BRITISH JOURNAL OF PSYCHIATRY; v. 197, n. 5, p. 378-385, NOV 2010.
Web of Science Citations: 658
Abstract

Background Although significant associations of childhood adversities with adult mental disorders are widely documented, most studies focus on single childhood adversities predicting single disorders. Aims To examine joint associations of 12 childhood adversities with first onset of 20 DSM-IV disorders in World Mental Health (WMH) Surveys in 21 countries. Method Nationally or regionally representative surveys of 51 945 adults assessed childhood adversities and lifetime DSM-IV disorders with the WHO Composite International Diagnostic Interview (CIDI). Results Childhood adversities were highly prevalent and interrelated. Childhood adversities associated with maladaptive family functioning (e.g. parental mental illness, child abuse, neglect) were the strongest predictors of disorders. Co-occurring childhood adversities associated with maladaptive family functioning had significant subadditive predictive associations and little specificity across disorders. Childhood adversities account for 29.8% of all disorders across countries. Conclusions Childhood adversities have strong associations with all classes of disorders at all life-course stages in all groups of WMH countries. Long-term associations imply the existence of as-yet undetermined mediators. (AU)

FAPESP's process: 03/00204-3 - Epidemiological study of psychiatric disorders in the São Paulo Metropolitan Region: prevalence, risk factors, and social and economical burden
Grantee:Laura Helena Silveira Guerra de Andrade
Support Opportunities: Research Projects - Thematic Grants