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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Low-fluoride toothpaste and deciduous enamel demineralization under biofilm accumulation and sucrose exposure

Full text
Author(s):
Cury, Jaime A. [1] ; do Amaral, Regiane C. [1] ; Tenuta, Livia M. A. [1] ; Cury, Altair A. Del Bel [1] ; Tabchoury, Cinthia P. M. [1]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, Piracicaba Dent Sch, BR-13414903 Piracicaba, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: European Journal of Oral Sciences; v. 118, n. 4, p. 370-375, AUG 2010.
Web of Science Citations: 29
Abstract

Because low-fluoride toothpaste (500 p.p.m. F) has not clearly been shown to be effective for controlling caries in caries-active children, this experimental in situ study was conducted to evaluate whether its effect, when compared with a conventional toothpaste (1,000-1,500 p.p.m. F), would depend on the cariogenic challenge. During four phases of 14 d each, 14 volunteers used 500 or 1,100 p.p.m. F toothpaste and wore palatal appliances containing deciduous enamel slabs, on which biofilm was accumulated and exposed to 20% sucrose solution at frequencies increasing from two to eight times per day. The F concentration was determined in the biofilm formed, and enamel demineralization was assessed by surface hardness loss (%SHL) and integrated area of hardness x lesion depth (Delta S). The F uptake by enamel was also determined. Fluoride in biofilm fluid and solids was statistically higher when conventional F toothpaste was used. The toothpastes did not differ statistically in terms of %SHL, Delta S, and F in enamel, but only the conventional F toothpaste significantly reduced caries-lesion progression according to the frequency of sucrose exposure. The findings suggest that the high-F availability in biofilm, resulting from the use of conventional toothpaste compared with low-F toothpaste, may be important for reducing caries-lesion progression in conjunction with a high frequency of sucrose exposure. (AU)

FAPESP's process: 07/05994-3 - Low fluoride dentifrice and deciduous enamel demineralization under high cariogenic challenge
Grantee:Regiane Cristina Do Amaral
Support Opportunities: Scholarships in Brazil - Master