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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Modulation of post-coital dopaminergic tone by prior parity

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Author(s):
Sider, Lucia Helena [1, 2] ; Teixeira da Silva Hucke, Erica Engelberg [1, 3] ; Felicio, Luciano Freitas [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Dept Patol, Sao Paulo - Brazil
[2] Embrapa Caprinos & Ovinos, Empresa Brasileira Pesquisa Agropecuaria, BR-62010970 Sobral, CE - Brazil
[3] Ctr Univ Fundacao Ensino Octavio Bastos, Sao Joao Da Boa Vista, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Brazilian Archives of Biology and Technology; v. 53, n. 3, p. 615-622, MAY-JUN 2010.
Web of Science Citations: 0
Abstract

The aim of this study was to investigate the possible effects of reproductive experience on dopaminergic profile in three different brain tissues, hypothalamus, striatum and cortex in rats on 7th-8th day of pregnancy during the light-dark shift (between 1700-1900h). Results showed that in hypothalamus, dopamine levels increased and DOPAC/DA decreased as a function of parity. In cortex, no differences were observed. In striata, the haloperidol-induced HVA and HVA/DA increases were less intense in experienced animals. These findings suggested that reproductive experience produced functional central changes during pregnancy, with different neurochemical responses depending on the brain region. (AU)