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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Low intensity laser (830 nm) functional to recover of the sciatic nerve in rats

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Author(s):
Marcolino, Alexandre Marcio [1] ; Barbosa, Rafael Inacio [1] ; Siqueira das Neves, Lais Mara [1] ; Vinas, Thomas Selvaggio [1] ; de Barros Duarte, Danilo Teixeira [1] ; Mazzer, Nilton [1] ; Registro Fonseca, Marisa de Cassia [1]
Total Authors: 7
Affiliation:
[1] USP, Fac Med Ribeirao Preto, Dept Biomech Med & Rehabil Locomotor Apparat, BR-14049900 Ribeirao Preto, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Acta Ortopédica Brasileira; v. 18, n. 4, p. 207-211, 2010.
Web of Science Citations: 9
Abstract

OBJECTIVE: This study aimed to evaluate the effect of low-intensity laser on functional improvement of the walking of rats after sciatic nerve axonotmesis. METHODS: We used 18 rats divided randomly in two groups: control (Sham) and irradiated with an energy density of 40J/cm² for 21 consecutive days, using 830nm laser (AsGaAl). The animals were subjected to right sciatic nerve crushing by a portable device and assessed by the "Sciatic Functional Index" (SFI) at an acrylic platform through video recorded by a digital camera. The footprints were collected preoperatively, and on the 7th, 14th and 21st postoperative days. RESULTS: The results of the SFI were significant when comparing the groups on the 7th and 14th postoperative day (p<0.05). On the 21st postoperative day there was no difference between groups. There were intra-group differences detected in each evaluated week (p<0.01). The irradiated animals showed improvement in motion pattern, shown by the SFI values in the initial periods, but after 3 weeks, there was a similar recovery. CONCLUSION: The low-intensity laser has shown to be effective in accelerating regeneration of the sciatic nerve of rats after crushing. (AU)