MOLECULAR CHARACTERIZATION OF Cryptosporidium spp. FROM HIV INFECTED PATIENTS FROM AN URBAN AREA OF BRAZIL

Author(s)

de Lucca, Patricia ^[1] ; De Gaspari, Elizabeth Natal ^[2] ; Bozzoli, Ligia M. ^[2] ; Funada, Mikaela Renata ^[1] ; de Souza Silva, Sheila Oliveira ^[1] ; Iuliano, Wilma ^[3] ; Soares, Rodrigo Martins ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Dept Med Vet Prevent & Saude Anim, BR-05508900 Sao Paulo - Brazil

^[2] Adolfo Lutz Inst, Immunol Sect, Sao Paulo - Brazil

^[3] Inst Emilio Ribas, Parasitol Lab, Sao Paulo - Brazil

• Document type: Journal article
• Source: Revista do Instituto de Medicina Tropical de São Paulo; v. 51, n. 6, p. 341-343, NOV-DEC 2009.
• Web of Science Citations: 8

Abstract

Cryptosporidium spp. are important cause of enteric disease in humans, but may also infect animals. This Study describes the relative frequency of several Cryptosporidium species found in human specimens from HIV infected patients in the Sao Paulo municipality obtained from January to July 2007. Sequence analysis Of file products of nested-PCR based on small subunit rRNA and Cryptosporidium oocyst wall protein coding genes revealed 17 (63.0%) isolates of C. hominis. four (14.8%) C. parvum, five (18.5%) C. felis and one (3.7%) C. canis. These findings suggest that, in Urban environments of Brazil. the cat adapted C. felis may play a potential role in the zoonotic transmission of cryptosporidiosis whereas the anthroponotic transmission of cryptosporidiosis caused by C. hominis seems to predominate. (AU)