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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

AMIN domains have a predicted role in localization of diverse periplasmic protein complexes

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Author(s):
de Souza, Robson Francisco [1, 2] ; Anantharaman, Vivek [3] ; de Souza, Sandro Jose [2] ; Aravind, L. [3] ; Gueiros-Filho, Frederico J. [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Dept Bioquim, Sao Paulo - Brazil
[2] Ludwig Inst Canc Res, Sao Paulo Branch, Sao Paulo - Brazil
[3] NIH, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 - USA
Total Affiliations: 3
Document type: Journal article
Source: Bioinformatics; v. 24, n. 21, p. 2423-2426, NOV 1 2008.
Web of Science Citations: 7
Abstract

We describe AMIN (Amidase N-terminal domain), a novel protein domain found specifically in bacterial periplasmic proteins. AMIN domains are widely distributed among peptidoglycan hydrolases and transporter protein families. Based on experimental data, contextual information and phyletic profiles, we suggest that AMIN domains mediate the targeting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. (AU)