| Full text | |
| Author(s): |
Chehoud, Keila Aziz
[1, 2]
;
Chiba, Fernando Yamamoto
[1, 2]
;
Sassaki, Kikue Takebayashi
[1]
;
Saliba Garbin, Clea Adas
[2]
;
Sumida, Doris Hissako
[1]
Total Authors: 5
|
| Affiliation: | [1] Sao Paulo State Univ UNESP, Dent Sch Aracatuba, Dept Basic Sci, BR-16015050 Aracatuba, SP - Brazil
[2] Sao Paulo State Univ UNESP, Dent Sch Aracatuba, Dept Child & Social Dent, BR-16015050 Aracatuba, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | FLUORIDE; v. 41, n. 4, p. 270-275, OCT-DEC 2008. |
| Web of Science Citations: | 11 |
| Abstract | |
Forty seven-week-old male castrated Wistar rats were randomly divided evenly into a control group and a fluoride (F) group. The latter was given a single dose of NaF from a solution containing 1.0 mg F ion/kg bw, administered by gavage. After 30 min, the following experiments were performed: intravenous insulin tolerance test (0.75 U/kg bw) and determination of the insulin receptor substrate (pp 185-IRS-1/IRS/2) tyrosine phosphorylation status. The acute treatment with NaF promoted increased blood glycemia, but there were no significant changes in the insulin sensitivity and in the pp185 tyrosine phosphorylation status in the muscular or in the white adipose tissues. (AU) | |