Effect of a single application of TiF4 and NaF varnishes and solutions on dentin erosion in vitro

Author(s)

Magalhaes, Ana Carolina ^[1] ; Levy, Flavia Mauad ; Rios, Daniela ^{[1, 2]} ; Rabelo Buzalaf, Marilia Afonso ^[1]

Affiliation

^[1] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, BR-17012910 Bauru, SP - Brazil

^[2] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Publ Hlth, BR-17012910 Bauru, SP - Brazil

• Document type: Journal article
• Source: Journal of Dentistry; v. 38, n. 2, p. 153-157, FEB 2010.
• Web of Science Citations: 23

Abstract

Objectives: This in vitro study aimed to analyse the effect of a single application of TiF(4) and NaF varnishes and solutions to protect against dentin erosion. Methods: Bovine root dentin samples were pre-treated with NaF-Duraphat varnish (2.26%F, pH 4.5), NaF/CaF(2)-Duofluorid varnish (5.63%F, pH 8.0), NaF-experimental varnish (2.45%F, pH 4.5), TiF(4)-experimental varnish (2.45%F, pH 1.2), NaF solution (2.26%F, pH 4.5), TiF(4) solution (2.45%F, pH 1.2) and placebo varnish (pH 5.0, no-F varnish control). Controls remained untreated. Ten samples in each group were then subjected to an erosive demineralisation (Sprite Zero, 4x 90 s/day) and remineralisation (artificial saliva, between the erosive cycles) cycling for S days. Dentin loss was measured profilometrically after pretreatment and after 1, 3 and 5 days of de-remineralisation cycling. The data were statistically analysed by two-way ANOVA and Bonferroni's post hoc test (p < 0.05). Results: After pre-treatment, TiF(4) solution significantly induced surface loss (1.08 +/- 0.53 mu m). Only Duraphat reduced the dentin loss overtime, but it did not significantly differ from placebo varnish (at 3rd and 5th days) and TiF(4) varnish (at 3rd day). Conclusions: Duraphat varnish seems to be the best option to partially reduce dentin erosion. However, the maintenance of the effects of this treatment after successive erosive challenges is limited. (C) 2009 Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 08/07105-4 - Evaluation of the effect of an experimental TiF4 varnish compared to NaF varnishes and solutions and to TiF4 solution on erosion and abrasion of enamel and dentin: in vitro and in situ studies
• Grantee: Ana Carolina Magalhães
• Support Opportunities: Regular Research Grants
• FAPESP's process: 08/03727-0 - Evaluation of the effect of an experimental titanium tetrafluoride varnish compared to sodium fluoride varnishes and solutions on erosion and abrasion of enamel and dentin in vitro and in situ
• Grantee: Flavia Mauad Levy Abrahão
• Support Opportunities: Scholarships in Brazil - Post-Doctoral