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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Counteractive effect of antacid suspensions on intrinsic dental erosion

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Turssi, Cecilia P. [1] ; Vianna, Lidia M. F. F. [1] ; Hara, Anderson T. [2] ; do Amaral, Flavia L. B. [1] ; Franca, Fabiana M. G. [1] ; Basting, Roberta T. [1]
Total Authors: 6
[1] Sao Leopoldo Mandic Res Ctr & Inst, Campinas, SP - Brazil
[2] Indiana Univ, Sch Dent, Oral Hlth Res Inst, Indianapolis, IN - USA
Total Affiliations: 2
Document type: Journal article
Source: European Journal of Oral Sciences; v. 120, n. 4, p. 349-352, AUG 2012.
Web of Science Citations: 11

This in vitro study aimed to investigate the anti-erosive effect of antacid suspensions applied to enamel after exposure to hydrochloric acid (HCl). Ninety bovine enamel slabs were embedded, flattened, and polished. Reference areas were created and specimens were divided into six groups. They were exposed to 0.01 M HCl (pH 2) for 2 min, followed by immersion for 1 min in one of the following test suspensions: magnesium hydroxide, aluminum hydroxide, magnesium hydroxide/aluminum hydroxide, sodium alginate/sodium bicarbonate/calcium carbonate, or hydrated magnesium aluminate. Artificial saliva was used as a negative control. Specimens were subjected to a total of five cycles of erosion/antacid treatment. Enamel surface loss was measured (in micrometers) by optical profilometry. In addition, baseline and final surface microhardness (SMH) values of enamel were obtained. It was found that antacid suspensions significantly reduced enamel loss, and that similar protection was afforded by all formulations. No differences were observed between the final enamel SMH values among groups. Antacid suspensions counteracted HCl-induced enamel loss, although they were not effective in reducing enamel softening. Mouth rinsing with antacid suspensions after vomiting can potentially represent a promising strategy to counteract enamel loss caused by erosion. (AU)

FAPESP's process: 11/02533-0 - Assessment of strategies to manage dental erosion caused by endogenous and exogenous acid sources
Grantee:Cecilia Pedroso Turssi
Support type: Regular Research Grants
FAPESP's process: 11/10789-5 - Control of dental erosion of intrinsic origin by oral suspensions with neutralizing potential
Grantee:Lidia Mendes Francisco Faria Vianna
Support type: Scholarships in Brazil - Scientific Initiation