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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effects of eating disorders on oral fungal diversity

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Author(s):
Back-Brito, Graziella Nuernberg [1] ; da Mota, Adolfo Jose [2] ; de Souza Bernardes, Luciano Angelo [3] ; Takamune, Silvia Satomi [4] ; Gomes Barbosa Prado, Eliane de Fatima [4] ; Cordas, Taki Athanassios [4] ; Balducci, Ivan [5] ; da Nobrega, Francisco Gorgonio [1] ; Koga-Ito, Cristiane Yumi [1]
Total Authors: 9
Affiliation:
[1] Univ Estadual Paulista, Sao Jose dos Campos Dent Sch, Dept Biosci & Oral Diag, Sao Jose Dos Campos - Brazil
[2] Univ Sao Paulo, Inst Biol Sci, Sao Paulo - Brazil
[3] Univ Sao Paulo, Fac Med, Dept Genet, Sao Paulo - Brazil
[4] Univ Sao Paulo, Fac Med, Inst Psychiat, Sao Paulo - Brazil
[5] Univ Estadual Paulista, Sao Jose dos Campos Dent Sch, Dept Social Dent, Sao Jose Dos Campos - Brazil
Total Affiliations: 5
Document type: Journal article
Source: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY; v. 113, n. 4, p. 512-517, APR 2012.
Web of Science Citations: 5
Abstract

Background. The eating disorders anorexia and bulimia nervosa can cause several systemic and oral alterations related to poor nutrition and induced vomiting; however, the oral microflora of these patients is poorly studied. Objective. The aim of this study was to evaluate fungal microflora in the oral cavity of these patients by culture-dependent and culture-independent methods. Study Design. Oral rinse samples were cultured to assess the prevalence of Candida species, and the isolates were identified by API system. Microorganism counts were compared by the Mann-Whitney test (5%). Ribotyping, a type of molecular analysis, was performed by sequencing the D1/D2 regions of 28S rRNA. Results. Our results demonstrated that the eating disorder group showed higher oral Candida spp. prevalence with culture-dependent methods and higher species diversity with culture-independent methods. Conclusions. Eating disorders can lead to an increased oral Candida carriage. Culture-independent identification found greater fungal diversity than culture-dependent methods. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;113:512-517) (AU)