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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Model-based assessment of baroreflex and cardiopulmonary couplings during graded head-up tilt

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Author(s):
Porta, Alberto [1] ; Bassani, Tito [1, 2] ; Bari, Vlasta [1] ; Tobaldini, Eleonora [3] ; Takahashi, Anielle C. M. [4] ; Catai, Aparecida M. [4] ; Montano, Nicola [3]
Total Authors: 7
Affiliation:
[1] Univ Milan, Dept Technol Hlth, Galeazzi Orthoped Inst, Milan - Italy
[2] Polytech Univ Milan, Dept Bioengn, Milan - Italy
[3] Univ Milan, Dept Clin Sci, L Sacco Hosp, Milan - Italy
[4] Univ Fed Sao Carlos, Dept Physiotherapy, BR-13560 Sao Carlos, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: COMPUTERS IN BIOLOGY AND MEDICINE; v. 42, n. 3, SI, p. 298-305, MAR 2012.
Web of Science Citations: 48
Abstract

We propose a multivariate dynamical adjustment (MDA) modeling approach to assess the strength of baroreflex and cardiopulmonary couplings from spontaneous cardiovascular variabilities. Open loop MDA (OLMDA) and closed loop MDA (CLMDA) models were compared. The coupling strength was assessed during progressive sympathetic activation induced by graded head-up tilt. Both OLMDA and CLMDA models suggested that baroreflex coupling progressively increased with tilt table inclination. Only CLMDA model indicated that cardiopulmonary coupling due to the direct link from respiration to heart period gradually decreased with tilt table angles, while that due to the indirect link mediated by systolic arterial pressure progressively increased. (C) 2011 Elsevier Ltd. All rights reserved. (AU)