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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of Nandrolone Decanoate on the Development of Three Species of Chrysomya (Diptera: Calliphoridae), Flies of Forensic Importance in Brazil

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Author(s):
Souza, C. M. [1] ; Thyssen, P. J. [1] ; Linhares, A. X. [1]
Total Authors: 3
Affiliation:
[1] Univ Estadual Campinas, UNICAMP, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Journal of Medical Entomology; v. 48, n. 1, p. 111-117, JAN 2011.
Web of Science Citations: 5
Abstract

Necrophagous insects are valuable tools for postmortem interval (PMI) estimation or for determining the cause of death. Due to the increase in deaths related to drug abuse, it is crucial to know how these substances affect the development of flies that feed on corpses, to avoid errors in the PMI estimates. This study evaluated the effect of nandrolone decanoate, an anabolic androgenic steroid, on the development of immatures of Chrysomya megacephala (F.), Chrysomya putoria (Wiedemann), and Chrysomya albiceps (Wiedemann) (Diptera: Calliphoridae) when added to an artificial rearing diet. Four experimental groups were delineated: three of them were given diets containing 4.5, 22.5, or 45 mg/kg nandrolone decanoate; and a drug-free control group. Weights were recorded at 12-h intervals from larval eclosion to pupation. No statistically significant differences were observed in mean larval weights, emergence interval, or emergence rates for all groups. However, differences in the three species were observed during the larval development. Initially, C. putoria reared in the highest concentration of decanoate showed greater weight gain. However, at older ages, immatures reached lower mean weights than the control group. For C. albiceps, the highest concentration of decanoate contributed to an effective lack of weight gain during almost the entire course of larval development. Therefore, the influence of any drug on development should always be considered. (AU)

FAPESP's process: 04/08544-0 - Forensic entomology: the use of Arthropods for determination of time, local, cause and circumstances of death
Grantee:Arício Xavier Linhares
Support Opportunities: Research Projects - Thematic Grants