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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Chemical Composition and Antioxidant and Antimycobacterial Activities of Bromelia balansae (Bromeliaceae)

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Author(s):
Coelho, Roberta Gomes [1] ; Honda, Neli Kika [1] ; Vieira, Maria do Carmo [2] ; Brum, Rosenei Louzada [1] ; Pavan, Fernando Rogerio [3] ; Fujimura Leite, Clarice Queico [3] ; Lima Cardoso, Claudia Andrea [4]
Total Authors: 7
Affiliation:
[1] Univ Fed Mato Grosso do Sul, Dept Chem, BR-79070900 Campo Grande, MS - Brazil
[2] Fed Univ Grande Dourados, Dept Agr, Dourados, MS - Brazil
[3] Univ Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, Sao Paulo - Brazil
[4] Univ Estadual Mato Grosso do Sul, Course Chem, Dourados, MS - Brazil
Total Affiliations: 4
Document type: Journal article
Source: JOURNAL OF MEDICINAL FOOD; v. 13, n. 5, p. 1277-1280, OCT 2010.
Web of Science Citations: 6
Abstract

Bromelia balansae (Family Bromeliaceae) is a medicinal plant commonly used in the central region of Brazil as a cough syrup and also eaten roasted. The methanolic extract of ripe fruits was analyzed by chromatographic methods and spectrometrically. Four glycoside flavonols were isolated: kaempferol-3-O-alpha-l-rhamnopyranoside (1), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-d-glucopyranoside (2), quercetin-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (3), and kaempferol 3,7-di-O-alpha-L-rhamnopyranoside (4). The resazurin microtiter assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis. The results showed a moderate activity of the methanolic extract with a minimal inhibitory concentration of 128 mu g/mL. Antioxidant activity was evaluated as free radical scavenging capacity and inhibition of peroxidation. Free radical scavenging capacity was assessed by measuring the scavenging activity of methanolic extract and methanolic fraction on 2,2-diphenyl-1-picrylhydrazyl radical. The methanolic extract showed low values of antioxidant activities, whereas the methanolic fraction exhibited free radical scavenging activity ranging from 20.2% to 91.1%, and the inhibition of peroxidation values ranging from 5.6% to 27.5%. This is the first chemical study reported in the literature about this species. (AU)

FAPESP's process: 08/10390-2 - Determination of pre-clinical profile in vitro and in vivo anti-tuberculosis activity of ruthenium(II)phosphine / picolinate complexes
Grantee:Fernando Rogério Pavan
Support Opportunities: Scholarships in Brazil - Doctorate