| Full text | |
| Author(s): |
Moura, Rodrigo A.
;
Sircili, Marcelo P.
[1]
;
Leomil, Luciana
;
Matte, Maria Helena
[2]
;
Trabulsi, Luiz R.
[1]
;
Elias, Waldir P.
[1]
;
Irino, Kinue
[3]
;
Pestana de Castro, Antonio F.
[4]
Total Authors: 8
|
| Affiliation: | [1] Butantan Inst, Bacteriol Lab, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Publ Hlth, Publ Hlth Lab, BR-05508900 Sao Paulo - Brazil
[3] Adolfo Lutz Inst, Sao Paulo - Brazil
[4] Univ Sao Paulo, Inst Ciencias Biomed, Dept Microbiol, Lab Human & Vet Bacteriol, BR-05508900 Sao Paulo - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Applied and Environmental Microbiology; v. 75, n. 23, p. 7399-7408, DEC 1 2009. |
| Web of Science Citations: | 41 |
| Abstract | |
Forty-nine typical and atypical enteropathogenic Escherichia coli (EPEC) strains belonging to different serotypes and isolated from humans, pets (cats and dogs), farm animals (bovines, sheep, and rabbits), and wild animals (monkeys) were investigated for virulence markers and clonal similarity by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). The virulence markers analyzed revealed that atypical EPEC strains isolated from animals have the potential to cause diarrhea in humans. A close clonal relationship between human and animal isolates was found by MLST and PFGE. These results indicate that these animals act as atypical EPEC reservoirs and may represent sources of infection for humans. Since humans also act as a reservoir of atypical EPEC strains, the cycle of mutual infection of atypical EPEC between animals and humans, mainly pets and their owners, cannot be ruled out since the transmission dynamics between the reservoirs are not yet clearly understood. (AU) | |
| FAPESP's process: | 04/12136-5 - Atypical enteropathogenetic Escherichia coli (atypical EPEC) |
| Grantee: | Waldir Pereira Elias Junior |
| Support Opportunities: | Research Projects - Thematic Grants |