One-Pot, Three-Step Reaction of 5-[(Trimethylsilyl)ethynyl]pyrrolidin-2-one with Azides Catalyzed by Cu-I: Synthesis of a Novel Class of 1,4-Disubstituted 1,2,3-Triazoles

Stefani, Helio A.; Ferreira, Fernando P.; Vieira, Adriano S.

Advanced search

Search - Use quotation marks to get a more specific result

Index

Field of knowledge

Start date

Betweenand

(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

One-Pot, Three-Step Reaction of 5-[(Trimethylsilyl)ethynyl]pyrrolidin-2-one with Azides Catalyzed by Cu-I: Synthesis of a Novel Class of 1,4-Disubstituted 1,2,3-Triazoles

Full text
Author(s):	Stefani, Helio A. ^[1] ; Ferreira, Fernando P. ^[2] ; Vieira, Adriano S. ^[3] Total Authors: 3
Affiliation:	^[1] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, BR-05508900 Sao Paulo - Brazil ^[2] Univ Fed Sao Paulo, Dept Biofis, BR-04023062 Sao Paulo - Brazil ^[3] Univ Estadual Campinas, Inst Quim, BR-13083866 Campinas, SP - Brazil Total Affiliations: 3
Document type:	Journal article
Source:	AUSTRALIAN JOURNAL OF CHEMISTRY; v. 65, n. 10, p. 1443-1450, 2012.
Web of Science Citations:	0
Abstract
A very fast, easy and efficient synthesis is described for a novel and biologically important class of 1,4-disubstituted-4-(5-pyrrolidin-2-one)-1,2,3-triazoles by an ultrasound-assisted one-pot, three-step click reaction sequence of 5-{[}(trimethylsilyl)ethynyl]pyrrolidin-2-one with organic azides mediated by catalytic Cu-I salts. (AU)

Short URL