| Full text | |
| Author(s): |
Cagnini, Didier Q.
[1]
;
Salgado, Breno S.
[2, 3]
;
Linardi, Juliana L.
[1]
;
Grandi, Fabrizio
[2, 4]
;
Rocha, Rafael M.
[5]
;
Rocha, Noeme S.
[1, 2]
;
Teixeira, Carlos R.
[1]
;
Del Piero, Fabio
[6]
;
Sequeira, Julio L.
[2]
Total Authors: 9
|
| Affiliation: | [1] Univ Estadual Paulista UNESP, Fac Med Vet & Zootecnia, Dept Clin Vet, Botucatu, SP - Brazil
[2] Univ Estadual Paulista UNESP, Fac Med Botucatu, Dept Patol, Botucatu, SP - Brazil
[3] FEPI, Curso Med Vet, Itajuba - Brazil
[4] Publ Vet Hosp, Dept Diagnost Pathol, Vet Serv, Natl Assoc Small Anim Clinicians Anclivepa, Sao Paulo - Brazil
[5] Hosp AC Camargo Fundacao Antonio Prudente, Dept Anat Patol, Sao Paulo - Brazil
[6] Louisiana State Univ, Sch Vet Med, Dept Pathobiol Sci, Baton Rouge, LA 70803 - USA
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | BMC Veterinary Research; v. 8, SEP 25 2012. |
| Web of Science Citations: | 6 |
| Abstract | |
Background: Reports of neoplasms in Panthera species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions. Case presentation: An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (Panthera leo). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver. Conclusions: This is the first description of these tumor in African lions. (AU) | |
| FAPESP's process: | 10/51596-2 - S100A4 and osteopontin immunoexpression evaluation in canine spontaneous mammary carcinomas |
| Grantee: | Noeme Sousa Rocha |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 09/53493-9 - In vitro expression of cyclooxygenase-2 (COX2) for osteosarcoma exposed to a COX2 selective inhibitor |
| Grantee: | Noeme Sousa Rocha |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 11/01610-1 - Evaluation of CD31, S100A4, and alpha SMA in the tumor microenvironment and their relation to endotelial-mesenchymal transition in canine spontaneous cutaneous melanomas |
| Grantee: | Noeme Sousa Rocha |
| Support Opportunities: | Regular Research Grants |