T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals

Iwai, Leo Kei; Yoshida, Márcia; Sadahiro, Aya; Silva, Washington Robert da; Marin, Maria Lucia; Goldberg, Anna Carla; Juliano, Maria Aparecida; Juliano, Luiz; Shikanai-Yasuda, Maria Aparecida; Kalil, Jorge; et al

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals

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Author(s): Show less -	Iwai, Leo Kei ; Yoshida, Márcia ; Sadahiro, Aya ; Silva, Washington Robert da ; Marin, Maria Lucia ; Goldberg, Anna Carla ; Juliano, Maria Aparecida ; Juliano, Luiz ; Shikanai-Yasuda, Maria Aparecida ; Kalil, Jorge ; et al Total Authors: 11
Document type:	Journal article
Source:	Clinical and Vaccine Immunology; v. 14, n. 4, p. 474-476, Apr. 2007.
Field of knowledge:	Biological Sciences - Immunology
Abstract
Vaccines with synthetic peptides induce the immune response to epitopes that bind to several HLA alleles. By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM. (AU)

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