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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Expression of the CTCF gene in bovine oocytes and preimplantation embryos

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Author(s):
Álvaro F.L. Rios [1] ; Daniela C. Lemos [2] ; Maurício B. Fernandes [3] ; Maria V. Andrea [4] ; Marcus V.M. Gomes [5] ; Raysildo B. Lôbo [6] ; Mendelson Mazucato [7] ; Ester S. Ramos
Total Authors: 8
Affiliation:
[1] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
[2] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
[3] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
[4] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
[5] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
[6] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
[7] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética
Total Affiliations: 8
Document type: Journal article
Source: GENETICS AND MOLECULAR BIOLOGY; v. 30, n. 4, p. 1202-1205, 2007-00-00.
Abstract

The CCCTC - binding factor (CTCF) is a protein involved in repression, activation, hormone-inducible gene silencing, functional reading of imprinted genes and X-chromosome inactivation. We analyzed CTCF gene expression in bovine peripheral blood, oocytes and in different cellular stages (2-4 cells, 8-16 cells, 16-32 cells, morulae, and blastocysts) of in vitro fertilized embryos. This is the first report of CTCF expression in oocytes and preimplantation bovine embryos and has implications for the production of embryonic stem cells and the development of novel medical technologies for humans. (AU)

FAPESP's process: 05/00616-5 - Differential development of XX and XY preimplantation embryos and TSPX and SRY gene expression pattern
Grantee:Ester Silveira Ramos
Support Opportunities: Regular Research Grants