| Full text | |
| Author(s): |
Simone Milani Brandão
[1]
;
Silvana Artioli Schellini
[2]
;
Carlos Roberto Padovani
[3]
;
Oscar Peitl
[4]
;
Emerson Hashimoto
[5]
Total Authors: 5
|
| Affiliation: | [1] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu - Brasil
[2] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu. Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - Brasil
[3] Universidade Estadual Paulista Júlio de Mesquita Filho. Instituto de Biociências. Departamento de Estatística - Brasil
[4] Universidade Federal de São Carlos. Departamento de Materiais - Brasil
[5] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu - Brasil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Rev. bras.oftalmol.; v. 72, n. 1, p. 21-25, 2013-02-00. |
| Abstract | |
OBJECTIVE: To evaluate bioglass, bioglassceramic biocompatibility in rabbit's eviscerated cavities. METHODS: Forty- five rabbits were submitted to right eye evisceration, followed by the inclusion of bioglass and bioglassceramic I e II prosthesis in the escleral cavity. The animals were sacrificed at seven, 90 and 180 days after surgery. The animals had daily clinical exam; biochemical exam, histological analysis and morphometric evaluation. RESULTS: The animals stayed healthy during the expriment, with good cone integration to the host tissue. None cone extrusion were observed. Histologically, it was observed pseudocapsule formation around the cones and the inflammatory reaction was higher at M1, getting progressively lower while getting at M3, being the lowest in rabbits which received bioglass cones (GA) than at any other groups. CONCLUSION: Bioglass and bioglassceramic I e II cones can be useful to repair anophthalmic cavity. (AU) | |
| FAPESP's process: | 08/08058-0 - Biocompatibility analysis of bioglass and bioceramic cones in anophthalmic eviscerated cavities in rabbits |
| Grantee: | Silvana Artioli Schellini |
| Support Opportunities: | Regular Research Grants |