Prevalence of Candida spp. during radiographic examination in Diabetes mellitus patients

Author(s)

Flávia Cristina Volpato ^[1] ; Juliana Rico Pires ^[2] ; Isis do Rosário da Costa Martinez ^[3] ; Silvana Regina Perez Orrico ^[4] ; Marciano Pires da Costa ^[5] ; Denise Madalena Palomari Spolidório ^[6] ; Andréa Gonçalves ^[7]

Affiliation

^[1] Univ Estadual Paulista. Faculdade de Odontologia - Brasil

^[2] Centro Universitário da Fundação Educacional de Barretos. Departamento de Periodontia e Implantodontia - Brasil

^[3] Univ Estadual Paulista. Faculdade de Odontologia - Brasil

^[4] Univ Estadual Paulista. Faculdade de Odontologia. Departamento de Diagnóstico e Cirurgia - Brasil

^[5] Univ Estadual Paulista. Faculdade de Ciências Farmacêuticas. Departamento de Bioquímica - Brasil

^[6] Univ Estadual Paulista. Faculdade de Odontologia. Departamento de Fisiologia e Patologia - Brasil

^[7] Univ Estadual Paulista. Faculdade de Odontologia. Departamento de Diagnóstico e Cirurgia - Brasil

• Document type: Journal article
• Source: Rev. odontol. UNESP; v. 42, n. 1, p. 13-19, 2013-02-00.

Abstract

INTRODUCTION: It is suggested that individuals with diabetes are more susceptible to Candida infections than healthy people, especially if periodontal infection is associated. OBJECTIVE: This study evaluated the prevalence of colonization by Candida spp. during radiographic examination in diabetic and non-diabetic patients. MATERIAL AND METHODS: Twenty-six patients with type 2 diabetes mellitus and 20 patients without diabetes mellitus, presenting chronic periodontitis and presence of Candida spp. in saliva were evaluated. During radiographic examination, samples of saliva were collected from: oral mucosa, conventional radiographic periapical film, digital x-ray sensor (CDR), and bite block of the receptor-positioning device. Colony forming units (cfu/mL) and identification of Candida yeasts were assessed. RESULT: Oral mucosa from both groups showed the highest colonization with Candida spp. if compared with others surfaces collected (p < 0.05). In diabetic patients, the mucosa of the upper left regions showed higher levels of colonization. In non-diabetic patients, the upper right molar region showed the highest level of colonization during the examination of the receptor-positioning device, the sensor and the non-sensitive film. Candida spp. levels in saliva were similar between diabetics (mean = 3.0 × 10(6)) and non-diabetics (mean = 3.8 × 10(6)). CONCLUSION: No difference in Candida spp. colonization (cfu/mL) in diabetics and non-diabetic patients was observed for the five collected surfaces and the simulated radiographic region. Candida albicans was the prevalent species of Candida spp. found on all the samples. (AU)