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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A differential diagnosis of inherited endocrine tumors and their tumor counterparts

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Author(s):
Toledo, Sergio P. A. [1] ; Lourenco, Jr., Delmar M. [1] ; Toledo, Rodrigo A. [2]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Fac Med, Endocrine Genet Unit LIM 25, Div Endocrinol, Sao Paulo - Brazil
[2] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 - USA
Total Affiliations: 2
Document type: Review article
Source: Clinics; v. 68, n. 7, p. 1039-1056, 2013.
Web of Science Citations: 8
Abstract

Inherited endocrine tumors have been increasingly recognized in clinical practice, although some difficulties still exist in differentiating these conditions from their sporadic endocrine tumor counterparts. Here, we list the 12 main topics that could add helpful information and clues for performing an early differential diagnosis to distinguish between these conditions. The early diagnosis of patients with inherited endocrine tumors may be performed either clinically or by mutation analysis in at-risk individuals. Early detection usually has a large impact in tumor management, allowing preventive clinical or surgical therapy in most cases. Advice for the clinical and surgical management of inherited endocrine tumors is also discussed. In addition, recent clinical and genetic advances for 17 different forms of inherited endocrine tumors are briefly reviewed. (AU)

FAPESP's process: 09/15386-6 - Analysis of the CDKN1A, CDKN1B, CDKN2B and CDKN2C genes in multiple endocrine neoplasias type 1 and 2.
Grantee:Rodrigo de Almeida Toledo
Support Opportunities: Scholarships in Brazil - Post-Doctoral