| Full text | |
| Author(s): |
Cardoso, Carmen Lucia
;
Bolzani, Vanderlan da Silva
[2]
;
Silva, Dulce Helena Siqueira
;
Ishii, Hideki
;
Berova, Nina
;
Nakanishi, Koji
Total Authors: 6
|
| Document type: | Journal article |
| Source: | Journal of Natural Products; v. 69, n. 7, p. 1046-1050, July. 2006. |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry |
| Abstract | |
An antioxidant, 1-(3',4'-dihydroxycinnamoyl) cyclopentane-2,3-diol [ or ( E)-2,3-dihydroxycyclopentyl-3-(3',4'-dihydroxyphenyl) acrylate ( 1)], and two known trans- and cis-chlorogenic acid methyl esters were isolated from the ethanolic extract of the leaves of Chimarrhis turbinata. The relative configuration of 1 was determined by NMR and by comparison of the circular dichroic spectrum ( CD) with those of the enantiomers of synthetic 3', 4'-dimethoxycinnamoyl analogues. The absolute configuration of one of the synthetic enantiomers was determined using the CD exciton chirality method. This established the structure of naturally occurring 1 as (E)- 2,3-dihydroxycyclopentyl- 3-(3', 4'-dihydroxyphenyl) acrylate. (AU) | |
| FAPESP's process: | 03/02176-7 - Conservation and sustainable use of the diversity from Cerrado and Atlantic Forest: chemical diversity and prospecting for potential drugs - phase II |
| Grantee: | Vanderlan da Silva Bolzani |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |