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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Virus-host interaction in feline immunodeficiency virus (FIV) infection

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Author(s):
Taniwaki, Sueli Akemi [1] ; Figueiredo, Andreza Soriano [2] ; Araujo, Jr., Joao Pessoa [3]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Prevent Vet Med & Anim Hlth, BR-05508270 Sao Paulo - Brazil
[2] Oswaldo Cruz Inst FIOCRUZ, Lab Viral Hepatitis, BR-21040360 Rio De Janeiro - Brazil
[3] Univ Estadual Paulista UNESP, Biosci Inst, Dept Microbiol & Imunol, BR-18618970 Botucatu, SP - Brazil
Total Affiliations: 3
Document type: Review article
Source: COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES; v. 36, n. 6, p. 549-557, DEC 2013.
Web of Science Citations: 5
Abstract

Feline immunodeficiency virus (FIV) infection has been the focus of several studies because this virus exhibits genetic and pathogenic characteristics that are similar to those of the human immunodeficiency virus (HIV), FIV causes acquired immunodeficiency syndrome (AIDS) in cats, nevertheless, a large fraction of infected cats remain asymptomatic throughout life despite of persistent chronic infection. This slow disease progression may be due to the presence of factors that are involved in the natural resistance to infection and the immune response that is mounted by the animals, as well as due to the adaptation of the virus to the host. Therefore, the study of virus-host interaction is essential to the understanding of the different patterns of disease course and the virus persistence in the host, and to help with the development of effective vaccines and perhaps the cure of FIV and HIV infections. (C) 2013 Elsevier Ltd. All rights reserved. (AU)