Synthesis of alpha-alkenyl-alpha-amino esters via addition of potassium Alkenyltrifluoroborate salts to imine in the presence of Yb(OTf)(3)

Stefani, Helio A.; Khan, Amna N.; Manarin, Flavia; Vendramini, Pedro H.; Eberlin, Marcos N.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of alpha-alkenyl-alpha-amino esters via addition of potassium Alkenyltrifluoroborate salts to imine in the presence of Yb(OTf)(3)

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Author(s):	Stefani, Helio A. ^[1] ; Khan, Amna N. ^[1] ; Manarin, Flavia ^[1] ; Vendramini, Pedro H. ^[2] ; Eberlin, Marcos N. ^[2] Total Authors: 5
Affiliation:	^[1] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, Sao Paulo - Brazil ^[2] Univ Estadual Campinas, Inst Quim, Campinas, SP - Brazil Total Affiliations: 2
Document type:	Journal article
Source:	Tetrahedron Letters; v. 54, n. 46, p. 6204-6207, NOV 13 2013.
Web of Science Citations:	5
Abstract
A simple protocol which led to an effective construction of alpha-alkenyl-alpha-amino esters was achieved under mild conditions. This transformation proceeded by Yb-catalyzed addition of alkenyltrifluoroborates across the imine double bond. A variety of functional groups could be applicable to both partners. (C) 2013 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process:	12/00424-2 - Synthesis of small libraries using potassium Organotrifluoroborates in Suzuki-Miyaura reactions
Grantee:	Helio Alexandre Stefani
Support Opportunities:	Research Projects - Thematic Grants


FAPESP's process:	10/15677-8 - Synthesis of alpha-substituted styrenes
Grantee:	Flávia Giovana Manarin
Support Opportunities:	Scholarships in Brazil - Post-Doctoral

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