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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evaluation of the antibacterial potential of Petroselinum crispum and Rosmarinus officinalis against bacteria that cause urinary tract infections

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Author(s):
Fernanda Villas Boas Petrolini [1] ; Rodrigo Lucarini [1] ; Maria Gorete Mendes de Souza [1] ; Regina Helena Pires [1] ; Wilson Roberto Cunha [2] ; Carlos Henrique Gomes Martins [1]
Total Authors: 6
Affiliation:
[1] Univ Franca, Lab Pesquisa Microbiol Aplicada, Nucleo Pesquisa Ciencias Exatas & Tecnol, Franca, SP - Brazil
[2] Univ Franca, Grp Pesquisa Prod Nat, Nucleo Pesquisa Ciencias Exatas & Tecnol, Franca, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Brazilian Journal of Microbiology; v. 44, n. 3, p. 829-834, 2013-12-17.
Abstract

In this study we evaluated the antibacterial activity of the crude hydroalcoholic extracts, fractions, and compounds of two plant species, namely Rosmarinus officinalis and Petroselinum crispum, against the bacteria that cause urinary tract infection. The microdilution method was used for determination of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The crude hydroalcoholic extract of R. officinalis displayed in vitro activity against Gram-positive bacteria, with satisfactory MBC for the clinical isolate S. saprophyticus. The fractions and the pure compound rosmarinic acid did not furnish promising results for Gram-negative bacteria, whereas fractions 2, 3, and 4 gave encouraging results for Gram-positive bacteria and acted as bactericide against S. epidermidis as well as E. faecalis (ATCC 29212) and its clinical isolate. R. officinalis led to promising results in the case of Gram-positive bacteria, resulting in a considerable interest in the development of reliable alternatives for the treatment of urinary infections. (AU)

FAPESP's process: 08/05140-7 - EVALUATION OF THE ANTIBACTERIAL POTENTIAL OF CRUDE EXTRACTS AND ISOLATED COMPOUNDS OF FLAVORING Petroselinum crispum and Rosmarinus officinalis AGAINST TO THE BACTERIA THAT CAUSES INFECTIONS URINARY TRACT
Grantee:Fernanda Villas Boas Petrolini
Support Opportunities: Scholarships in Brazil - Scientific Initiation