| Full text | |
| Author(s): |
Soares Neto, Julino A. R.
[1]
;
Galduroz, Jose Carlos F.
[2]
;
Marques, Luis Carlos
[3]
;
Kato, Edna Tomiko
[4]
;
Macrini, Thiago
[4]
;
Rodrigues, Eliana
[5]
Total Authors: 6
|
| Affiliation: | [1] Univ Fed Sao Paulo, Dept Prevent Med, Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil
[3] Univ Bandeirantes Sao Paulo, Pharm Program, Sao Paulo - Brazil
[4] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Pharm, Sao Paulo - Brazil
[5] Univ Fed Sao Paulo, Dept Biol Sci, Ctr Ethnobot & Ethnopharmacol Studies, Sao Paulo - Brazil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Phytotherapy Research; v. 28, n. 3, p. 405-411, MAR 2014. |
| Web of Science Citations: | 2 |
| Abstract | |
The present study aimed to investigate the occurrence of adverse reactions (ADRs) related to herbal products (HPs), which are purchased over-the-counter for self-treatment, reported by 100 users. Samples of the HPs related to those ADRs were purchased for their pharmacobotanical identification. The ADRs reported were evaluated based on specialized literature and were analyzed according to causality into probable (PR), possible (PO), unrelated (UR) or unclassifiable (UC); according to expectance into unexpected adverse reaction (UNEX) and expected adverse reaction (EX); seriousness into serious adverse event or reaction (S) and non-serious (NS); and severity into mild (MI), moderate (MO) and severe (SE). Among 100 interviews, five complaints of ADRs were reported in relation to HPs: Senna alexandrina, with a report of cramps (PR; MI; EX; NS); Camellia sinensis, associated with tachycardia (PO; MI; EX; NS); Bauhinia sp., a strong allergic reaction that led to hospitalization (UC; MO; UNEX; S); Picrasma crenata, with several symptoms and hospitalization (UR; MO; UNEX; S); and 21-herb tea, related to an allergic reaction (UC; MI; EX; NS). The strategies used in this study allowed us to carry out an analysis of ADRs attributed to HPs. This analysis could serve as a model in the study of similar cases. Copyright (c) 2013 John Wiley \& Sons, Ltd. (AU) | |