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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Adhesion of Candida biofilm cells to human epithelial cells and polystyrene after treatment with silver nanoparticles

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Author(s):
Monteiro, Douglas Roberto [1, 2] ; Negri, Melyssa [1, 3] ; Silva, Sonia [1] ; Gorup, Luiz Fernando [4] ; de Camargo, Emerson Rodrigues [4] ; Oliveira, Rosario [1] ; Barbosa, Debora Barros [2] ; Henriques, Mariana [1]
Total Authors: 8
Affiliation:
[1] Univ Minho, Inst Biotechnol & Bioengn, Dept Biol Engn, P-4710057 Braga - Portugal
[2] Univ Estadual Paulista, UNESP, Aracatuba Dent Sch, Dept Dent Mat & Prosthodont, BR-16015050 Sao Paulo - Brazil
[3] Fac INGA, BR-87070000 Maringa, Parana - Brazil
[4] Fed Univ Sao Carlos UFSCar, LIEC Dept Chem, BR-13565905 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: COLLOIDS AND SURFACES B-BIOINTERFACES; v. 114, p. 410-412, FEB 1 2014.
Web of Science Citations: 5
Abstract

This study investigated the adhesion to human epithelial cells and polystyrene surface of viable yeasts recovered from Candida biofilms treated with silver nanoparticles (SN). Biofilm resuspended Candida cells were added to HeLa cells or to empty wells of microtiter plates and the adhesion was verified using crystal violet staining. The adhesion of Candida cells was significantly reduced, mainly when biofilms were pretreated with 54 mu g/mL SN. These new findings allow to conclude that SN may induce changes in viable yeasts, which can decrease the dissemination of Candida infections, mainly in susceptible patients. (C) 2013 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 09/15146-5 - Effect of silver nanoparticles on Candida spp. biofilm
Grantee:Douglas Roberto Monteiro
Support Opportunities: Scholarships in Brazil - Doctorate