Prevalence of sarcopenia and associated risk factors by two diagnostic criteria in community-dwelling older men: the So Paulo Ageing & Health Study (SPAH)

Author(s)

Figueiredo, C. P. ^[1] ; Domiciano, D. S. ^[1] ; Lopes, J. B. ^[1] ; Caparbo, V. F. ^[1] ; Scazufca, M. ^[2] ; Bonfa, E. ^[1] ; Pereira, R. M. R. ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Med, Bone Metab Lab, Div Rheumatol, BR-01246903 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Fac Med, Dept Psychiat, BR-01246903 Sao Paulo - Brazil

• Document type: Journal article
• Source: OSTEOPOROSIS INTERNATIONAL; v. 25, n. 2, p. 589-596, FEB 2014.
• Web of Science Citations: 23

Abstract

Sarcopenia is an aging syndrome that can be characterized by many criteria adjusted or not by fat mass. This study suggested that the optimal criteria should be selected according to body mass index (BMI) in older men and identified age, BMI, race, smoking, physical activity, hip bone mineral density (BMD) as risk factors for this syndrome. This study aims to analyze the prevalence of sarcopenia and associated risk factors using appendicular skeletal mass (ASM)/height(2) and ASM adjusted for total fat mass criteria in older men from community. Three hundred ninety-nine men were included and answered a questionnaire about lifestyle and medical history. Individuals were classified by their BMI using the classification adjusted by age. Body composition and bone mineral density were measured by dual X-ray absorptiometry. Sarcopenia was classified according to both criteria. Logistic regression models were used to analyze risk factors associated with sarcopenia. The mean BMI was 26.46 kg/m(2): 12.5 % underweight, 43.6 % normal, and 43.9 % overweight/obese. Fifty-four (13.5 %) were considered sarcopenic by ASM/height(2) and 79 (19.8 %) by ASM adjusted for fat (p = 0.001). Fifty-one (12.8 %) individuals had discordant sarcopenia classification: 13 were classified only by ASM/height(2) and 38 only by ASM adjusted for fat. Of the 13 subjects classified as sarcopenic only by ASM/height(2), 84.6 % (11/13) were underweight and solely one (7.7 %) was considered overweight/obese. In contrast, of those 38 older men classified as sarcopenic only by ASM adjusted for fat, none were underweight and 53 % (20/38) were overweight/obese. Subjects classified as sarcopenic according to both criteria had the same risk factors in the final model analyses (age, BMI, race, smoking, physical activity, hip BMD; p < 0.05). This study suggested that the optimal criteria for sarcopenia should be selected according to BMI in community-dwelling older men. (AU)

• FAPESP's process: 03/09313-0 - Prevalence of osteoporosis, vertebral and non-vertebral fractures in a female population aged 65 or older in the Butantã area
• Grantee: Rosa Maria Rodrigues Pereira
• Support Opportunities: Regular Research Grants
• FAPESP's process: 04/12694-8 - Incidence of dementia and cognitive decline in low-income elderly in São Paulo: a cohort study
• Grantee: Isabela Judith Martins Bensenor
• Support Opportunities: Regular Research Grants