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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Influence of creatine supplementation on indicators of glucose metabolism in skeletal muscle of exercised rats

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Author(s):
de Araujo, Michel Barbosa [1] ; Vieira Junior, Roberto Carlos [2] ; de Moura, Leandro Pereira [1] ; Costa Junior, Marcelo [1] ; Dalia, Rodrigo Augusto [1] ; da Silva Sponton, Amanda Christine [1] ; Ribeiro, Carla [1] ; Rostom de Mello, Maria Alice [1]
Total Authors: 8
Affiliation:
[1] Sao Paulo State Univ Rio Claro, Rio Claro, SP - Brazil
[2] Univ Fed Mato Grosso, Cuiaba - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Motriz: rev. educ. fis.; v. 19, n. 4, p. 709-716, 2013.
Web of Science Citations: 1
Abstract

The purpose of this study was to evaluate the effect of creatine supplementation in the diet on indicators of glucose metabolism in skeletal muscle of exercised rats. Forty Wistar adult rats were distributed into four groups for eight weeks: 1) Control: sedentary rats that received balanced diet; 2) Creatine control: sedentary rats that received supplementation of 2% creatine in the balanced diet; 3) Trained: rats that ran on a treadmill at the Maximal Lactate Steady State and received balanced diet; and 4) Supplemented-trained: rats that ran on a treadmill at the Maximal Lactate Steady State and received creatine supplementation (2%) in the balanced diet. The hydric intake increased and the body weight gain decreased in the supplemented-trained group. In the soleus muscle, the glucose oxidation increased in both supplemented groups. The production of lactate and glycemia during glucose tolerance test decreased in the supplemented-trained group. Creatine supplementation in conjunction with exercise training improved muscular glycidic metabolism of rats. (AU)