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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Dietary polyunsaturated fatty acid intake during late pregnancy affects fatty acid composition of mature breast milk

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Author(s):
Nishimura, Renata Y. [1] ; Barbieiri, Patricia [1] ; de Castro, Gabriela S. F. [2] ; Jordao, Jr., Alceu A. [3] ; Castro Perdonda, Gleici da Silva [4] ; Sartorelli, Daniela S. [4]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Program Community Hlth, Sao Paulo - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Med Sch, Program Internal Med, Sao Paulo - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Sao Paulo - Brazil
[4] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Social Med, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: NUTRITION; v. 30, n. 6, p. 685-689, JUN 2014.
Web of Science Citations: 11
Abstract

Objective: The aim of this study was to investigate how maternal polyunsaturated fatty acid intake at different periods during pregnancy affects the composition of polyunsaturated fatty acids in mature human milk. Methods: A prospective study was conducted involving 45 pregnant women, aged between 18 and 35y, who had full-term pregnancies and practiced exclusive or predominant breast-feeding. Mature breast milk samples were collected after the 5th postpartum week by manual expression; fatty acid composition was determined by gas chromatography. Fatty acid intake during pregnancy and puerperium was estimated through multiple 24-h dietary recalls. Linear regression models, adjusted by postpartum body mass index and deattenuated, were used to determine associations between estimated fatty acids in maternal diet during each trimester of pregnancy and fatty acid content in mature human milk. Results: A positive association was identified between maternal intake of eicosapentaenoic acid (beta, 1.873; 95% confidence interval {[}CI], 0.545, 3.203) and docosahexaenoic acid (beta, 0.464; 95% CI, 0.212-0.714) during the third trimester of pregnancy, as well as the maternal dietary omega-3 to omega-6 ratio (beta, 0.093; 95% CI, 0.016-0.170) during the second and third trimesters and postpartum period, with these fatty acids content in mature breast milk. Conclusions: The maternal dietary docosahexaenoic acid and eicosapentaenoic acid content during late pregnancy may affect the fatty acid composition of mature breast milk. Additionally, the maternal dietary intake of omega-3 to omega-6 fatty acid ratio, during late pregnancy and the postpartum period, can affect the polyunsaturated fatty acid composition of breast milk. (C) 2014 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 10/12320-1 - Influence of the maternal food intake on fatty acids composition of mature human milk
Grantee:Renata Yumi Nishimura
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 10/00408-1 - Effects of Fish Oil N-3 Fatty Acids on Lipid Metabolism and Gene Expression in Rats Fed a High-Fructose Diet
Grantee:Gabriela Salim Ferreira de Castro
Support Opportunities: Scholarships in Brazil - Doctorate