Short Report: Heterogeneity of Leishmania infantum chagasi Kinetoplast DNA in Teresina (Brazil)

Alonso, Diego Peres; Costa, Dorcas Lamounier; de Mendonca, Ivete Lopes; Nery Costa, Carlos Henrique; Martins Ribolla, Paulo Eduardo

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Short Report: Heterogeneity of Leishmania infantum chagasi Kinetoplast DNA in Teresina (Brazil)

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Author(s):	Alonso, Diego Peres ; Costa, Dorcas Lamounier ^[2] ; de Mendonca, Ivete Lopes ^[3] ; Nery Costa, Carlos Henrique ^[4] ; Martins Ribolla, Paulo Eduardo Total Authors: 5
Document type:	Journal article
Source:	American Journal of Tropical Medicine and Hygiene; v. 82, n. 5, p. 819-821, MAY 2010.
Web of Science Citations:	1
Abstract
Leishmania infantum chagasi is the causative agent of visceral leishmaniasis in Brazil. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of kinetoplast DNA (kDNA) minicircles was used to evaluate genetic profiles of 48 Leishmania infantum chagasi strains from dog and human parasite cultures, fresh collected dog bone marrow aspirates, and from infected sand flies. Results revealed that heterogeneity in kDNA minicircles depends mostly on the source of the samples, with cultured parasites showing a high degree of homogeneity. (AU)

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