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Towards the development of a public and environmental health early warning system via water fingerprinting in Brazil

Grant number: 19/23352-6
Support type:Regular Research Grants
Duration: April 01, 2020 - March 31, 2022
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Cooperation agreement: University of Bath
Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
Principal Investigator:Cassiana Carolina Montagner
Grantee:Cassiana Carolina Montagner
Principal investigator abroad: Barbara Kasprzyk-Hordern
Institution abroad: University of Bath, England
Home Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:18/21733-0 - Microplastics as transport vectors of organic emerging contaminants in Brazilian aquatic matrices, AP.R

Abstract

We will engage in a new collaborative endeavor between key chemical pollution experts in the UK and Brazil to tackle public health problems linked with urbanization and deteriorating environment via water fingerprinting. This will be achieved via large-scale environment fingerprinting program in Campinas. We will focus on public exposure and environmental impacts from consumer, lifestyle and industrial chemicals. These include endocrine disruptors (such as UV filters, BPA), antimicrobial agents, pesticides, pharmaceuticals and lifestyle chemicals. Several biomarker groups spanning across genes, small organic molecules and proteins will be targeted: (1) Biomarkers of exposure to various xenobiotic micro-pollutants (industrial waste products, household chemicals, and endogenous human metabolism products) (2) Microbial biomarkers (e.g. genes, including resistance genes) (3) Characteristic endogenous biomarkers representing communities' health including oxidative stress biomarkers (e.g. DNA damage: 8-OHdG, 8-NO2Gua) and lipid peroxidation (8-IsoPGF2a and HNE-MA) with the aim of identifying hotspots for environmental degradation (5) Physical/generic indicators (e.g. pH, T, COD, etc) (6) plastics, to understand dynamics with city systems. (AU)