Towards the development of a public and environmental health early warning system via water fingerprinting in Brazil

• Grant number: 19/23352-6
• Support Opportunities: Regular Research Grants
• Duration: April 01, 2020 - March 31, 2023
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Convênio/Acordo: University of Bath
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Cassiana Carolina Montagner
• Grantee: Cassiana Carolina Montagner
• Principal researcher abroad: Barbara Kasprzyk-Hordern
• Institution abroad: University of Bath, England
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 18/21733-0 - Microplastics as transport vectors of organic emerging contaminants in Brazilian aquatic matrices, AP.R

Abstract

We will engage in a new collaborative endeavor between key chemical pollution experts in the UK and Brazil to tackle public health problems linked with urbanization and deteriorating environment via water fingerprinting. This will be achieved via large-scale environment fingerprinting program in Campinas. We will focus on public exposure and environmental impacts from consumer, lifestyle and industrial chemicals. These include endocrine disruptors (such as UV filters, BPA), antimicrobial agents, pesticides, pharmaceuticals and lifestyle chemicals. Several biomarker groups spanning across genes, small organic molecules and proteins will be targeted: (1) Biomarkers of exposure to various xenobiotic micro-pollutants (industrial waste products, household chemicals, and endogenous human metabolism products) (2) Microbial biomarkers (e.g. genes, including resistance genes) (3) Characteristic endogenous biomarkers representing communities' health including oxidative stress biomarkers (e.g. DNA damage: 8-OHdG, 8-NO2Gua) and lipid peroxidation (8-IsoPGF2a and HNE-MA) with the aim of identifying hotspots for environmental degradation (5) Physical/generic indicators (e.g. pH, T, COD, etc) (6) plastics, to understand dynamics with city systems. (AU)